Expression of a medaka (Oryzias latipes) Bar homologue in the differentiating central nervous system and retina

摘要

The Bar homcobox genes play an essential role during nervous system and eye development in Drosophila. We isolated a medaka Bar gene closely related to the Drosophila and mammalian Bar genes. In the medaka embryo, OlBar is expressed from gastrula stages onwards, in a re-ion demarcating the presumptive prosencephalic-mesencephalic boundary. Later in development, OlBar transcripts are found in populations of differentiating neuronal cells of the brain and the retina.